Some Ozempic users are reporting a surprising side effect — a loss of interest in masturbation and lower libido. The drug, originally approved for type 2 diabetes, is widely used off-label for weight loss. Its active ingredient, semaglutide, helps reduce appetite, but may also affect sexual desire.
Social media users have described feeling less interested in porn or masturbation after starting Ozempic. “I was addicted before, now I barely think about it,” one person wrote. Others say their sex drive is slightly lower, but still normal.

Experts believe the changes could be linked to rapid weight loss, which can temporarily stress the body. “Most patients improve within weeks,” said Dr. Eric Smith. He recommends adjusting the dose if needed.
Doctors also suggest healthy habits like regular exercise, better sleep, and open communication with partners. These can help boost mood and libido. While research is still ongoing, patients should always report side effects to their doctor or pharmacist.
Novo Nordisk, the maker of Ozempic, continues to monitor reports and advises all use under medical supervision.