Millions use weight loss drugs like Wegovy and Mounjaro to manage obesity and diabetes. But experts now warn many people regain pounds once they stop the injections.
Research shows patients often put back two-thirds of their lost weight after treatment ends. “Weight management is a long-term journey, not a short-term fix,” said Dr. Rebecca Payne of NICE.

Trials in both the U.S. and China found patients quickly gained weight within weeks of stopping the jabs. Doctors stress the importance of ongoing support, including nutrition advice, walking groups, and healthy lifestyle changes. “The transition period after treatment is crucial,” explained Professor Jonathan Benger.
Health leaders want new care standards to ensure people are guided after coming off the medication. This includes practical tips for home and work life, plus access to community support.
This reminder is clear: medication may help start weight loss, but lasting change requires daily habits. Do you think more support should be offered once treatments stop?