Doctors are warning that pain, swelling, redness, and warmth in one leg could be more serious than they seem. These common symptoms might signal deep vein thrombosis (DVT) — and, in some cases, pancreatic cancer.
Experts say a blood clot in the leg can sometimes be the first sign of cancer developing deep inside the body. “A clot can be the body’s early alarm that something isn’t right,” medical researchers explain. If the clot travels to the lungs, it can cause a pulmonary embolism, which can be life-threatening.

Pancreatic cancer is one of the most dangerous forms, often showing few symptoms until it spreads. Other warning signs include fatigue, yellowing skin or eyes, darker urine, pale stools, and unexplained weight loss.
Doctors urge people not to ignore persistent or unusual symptoms. Early testing can save lives. If you notice swelling or pain in your leg without clear reason, seek medical advice immediately — your body may be warning you.