Millions take acid reflux pills like omeprazole, but experts warn of hidden risks.
Pharmacist Deborah Grayson says these drugs may help short-term, but harm digestion in the long run. “We need stomach acid to break down food and absorb nutrients,” she explained.

Omeprazole belongs to a group called proton pump inhibitors (PPIs). They reduce stomach acid, easing heartburn and reflux. But long-term use may cause bloating, nausea, weight changes, and vitamin deficiencies. Low acid can also raise infection risk and weaken the body’s natural defenses.

Acid reflux happens when stomach acid flows back into the throat, often after eating quickly or eating trigger foods like chocolate, coffee, or spicy meals. While PPIs can help if you have severe inflammation, lifestyle changes may work better for mild heartburn. Eating slowly, avoiding late-night meals, and limiting trigger foods can make a big difference.

Grayson warns that “we are sleepwalking into a culture of PPI addiction.” She urges patients to seek an exit plan and talk to their doctor. Sometimes, the best medicine is changing how — and what — we eat.