Ozempic and other GLP-1 drugs like Mounjaro and Wegovy are making headlines for their weight loss benefits. Originally designed to treat type 2 diabetes, they’ve surged in popularity—especially among celebrities—for their appetite-suppressing effects.

But what many don’t know is that these medications carry the FDA’s most serious warning: a boxed warning. This label highlights potentially life-threatening risks, including a concerning link to thyroid tumors. Animal studies showed a connection to thyroid cancer, prompting the warning. The FDA advises against taking these drugs if you have a personal or family history of such cancers.

Still, new research from 2024 offers some reassurance. It found no strong evidence of increased thyroid cancer risk in humans taking GLP-1 drugs, though it didn’t entirely rule out a small risk.

Experts urge caution. Dr. Kristopher Day emphasized that newer studies benefit from better tools and longer follow-up. However, before using drugs like Ozempic, it’s crucial to talk with your doctor.

These medications can be effective, but they’re not risk-free—so stay informed before starting.