Weight loss drugs like Mounjaro are growing in popularity. The weekly injection works by controlling blood sugar, appetite, and how the body uses insulin. Dr. Donald Grant, a GP and clinical advisor, explained what people can expect in those first weeks.

In week one, users may feel nervous. Some notice reduced appetite within days. Common side effects include nausea, headaches, indigestion, or diarrhea, but these usually ease as the body adjusts. “It’s important to read the instructions carefully so you know exactly how the injection works,” Dr. Grant advised.

By week two, many people report fewer cravings for fatty or sugary foods. Some also feel fuller for longer. “It’s a good sign, but dehydration and fatigue can follow if you’re eating less,” Dr. Grant warned. Staying hydrated and eating balanced meals is key.

After four weeks, most side effects fade and appetite is consistently reduced. On average, people lose under 4% of body weight in the first month. Dr. Grant stressed: “Healthy eating and exercise matter most for long-term results.”

While Mounjaro can help with weight loss, lifestyle changes remain the true foundation of lasting health.