Doctors are warning about a possible link between popular weight-loss drugs and sudden vision loss.
New reports describe nine US patients who experienced serious eye problems after taking medications containing semaglutide or tirzepatide, the active ingredients in drugs such as Ozempic and Mounjaro. Some patients developed sudden blindness in one or both eyes.
Most were diagnosed with a condition called nonarteritic ischemic anterior optic neuropathy (NAION). This occurs when blood flow to the optic nerve is reduced, leading to rapid vision loss. NAION is more common in people with diabetes, high blood pressure, or sleep apnea.
Researchers say it is not yet clear whether the drugs directly caused the problem. One theory is that these medications can rapidly lower blood sugar levels, which may affect blood vessels in the eyes.
In several cases, vision improved after patients stopped taking the medication. However, the studies do not prove a direct cause-and-effect link.
Health authorities are now reviewing the safety data. Medical experts are not advising patients to stop treatment on their own, but they urge anyone who experiences sudden changes in vision to seek medical care immediately.
These medications are widely used for diabetes and weight management. While serious side effects appear to be rare, doctors say patients should be aware of potential risks and discuss concerns with their healthcare provider.