A California mother who became a symbol of strength after losing all three of her young children in a car crash has died from aggressive brain cancer at the age of 48.
Lori Coble came to national attention in 2007 after a truck crashed into her family’s vehicle, killing her three small children. The tragedy deeply affected people across the US and left Lori and her husband facing unimaginable grief.

Despite the loss, Lori slowly rebuilt her life. About a year later, she and her husband welcomed triplets, which helped them move forward. In later years, she spoke openly about grief, forgiveness, and resilience, offering comfort to many families who had experienced loss.
In mid-2025, Lori’s health began to deteriorate. Her husband noticed changes in her coordination and movement, which led to medical tests. Doctors diagnosed her with an aggressive form of brain cancer that progressed rapidly.

Lori chose to fight the illness and underwent surgery and treatment, hoping to gain more time with her family. As her condition worsened, she entered hospice care and died peacefully, surrounded by loved ones.
Her family and friends say she will be remembered as a devoted mother whose strength, kindness, and courage inspired people across the country.
