Scientists in Spain have reported a major breakthrough in pancreatic cancer research after successfully eliminating the disease in laboratory mice. The study was carried out by researchers at the Spanish National Cancer Research Centre and published in a leading scientific journal.
Pancreatic cancer is one of the deadliest forms of cancer, with very low long-term survival rates. One reason it is so hard to treat is a genetic mutation called KRAS, which is found in most pancreatic cancer cases and often becomes resistant to treatment.
The research team, led by Mariano Barbacid, used an experimental approach that targets the KRAS mutation in three different ways at the same time. By attacking the cancer on multiple fronts, the tumor was unable to adapt or become resistant.
When tested in mice, the treatment completely removed pancreatic tumors and prevented them from returning. The researchers reported no major side effects during the study. They described the results as a permanent disappearance of the cancer in these experimental models.
A team of scientists from the Spanish Cancer Research Centre, led by the renowned Dr Mariano Barbacid, has achieved the complete and permanent disappearance of pancreatic cancer in experimental models.
— Embassy of Spain UK (@EmbSpainUK) January 28, 2026
This discovery could make a difference in the fight against this disease. 👏 pic.twitter.com/gcnn1hPKBk
Experts stress that this does not yet mean a cure for people. Human trials have not started, and more research is needed before the treatment can be safely tested in patients. However, scientists say the findings open the door to future therapies that could significantly improve outcomes for pancreatic cancer patients.
The discovery is being seen as a hopeful step forward against one of the most aggressive cancers.