A new educational video from Carleton University is drawing attention for its clear explanation of how cannabis affects the brain and why regular use may lead to troubling health problems. The simulation breaks down how the drug creates a “high” and how long-term use may contribute to issues such as anxiety, depression, memory problems, and, in some cases, psychosis.

The video focuses on the body’s endocannabinoid system, which helps regulate mood, stress, and memory. Under normal conditions, the brain produces its own signaling chemicals, called endocannabinoids, that attach to specific receptors. These natural chemicals help keep emotional and cognitive functions balanced.

When someone uses cannabis, THC—the drug’s main psychoactive ingredient—binds to the same receptors. This triggers a surge of dopamine, which creates the feeling of euphoria. However, researchers say that frequent exposure to THC can cause the brain to dial back its own endocannabinoid production. Over time, this shift may make some people more vulnerable to anxiety, depression, and other mental health concerns.

Doctors are also warning about a physical condition tied to long-term use: cannabis hyperemesis syndrome (CHS). This illness causes repeated episodes of intense nausea and vomiting. Emergency physician Dr. Chris Buresh notes that even people who have used cannabis for years without trouble may suddenly develop symptoms. For some, the reaction can start after only small amounts.

Scientists believe each person has a different threshold for developing CHS or other complications, which makes predicting risk difficult. Still, experts agree that regular and long-term cannabis use increases the chances of both mental and physical side effects.

The video’s message is straightforward: while occasional use may seem harmless, consistent cannabis consumption can lead to significant changes in the brain and may trigger serious health problems in certain individuals.