Scientists have discovered a potential reason why colon cancer is rising in younger adults. Research from UT Southwestern shows that in younger patients, colon tissue often becomes unusually stiff and rigid. This physical change appears to create a “speed trap” for health, causing cells to multiply faster and increasing the risk of dangerous mutations.
The study found that chronic inflammation is the likely culprit. This inflammation alters collagen, the protein that gives our organs structure, making it dense and tough rather than flexible. While the exact trigger for this inflammation is still being studied, experts point to common lifestyle factors like poor diet, lack of sleep, and smoking as probable contributors.
This discovery is a major step forward in understanding “early-onset” colon cancer, which has increased by 50% in younger age groups over the last thirty years. By focusing on the stiffness of the tissue, doctors may soon have new ways to identify high-risk individuals before cancer even develops.
For those over 45, this research reinforces the importance of managing inflammation through healthy habits. Maintaining a balanced microbiome and a good diet remains one of the best ways to keep the digestive system flexible and healthy.
Researchers hope these findings will lead to new treatments that target the mechanical stiffness of the colon, potentially stopping the disease in its tracks.